Lymphotoxin limits Foxp3+ regulatory T cell development from Foxp3lo precursors via IL-4 signaling-Reference-Cited by-同舟云学术

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Lymphotoxin limits Foxp3+ regulatory T cell development from Foxp3lo precursors via IL-4 signaling

Published:2024-08-14 Issue:1 Volume:15 Page:
ISSN:2041-1723
Container-title:Nature Communications
language:en
Short-container-title:Nat Commun

Author:

Borelli Alexia^ORCID,Santamaria Jérémy C.^ORCID,Zamit Cloé^ORCID,Apert Cécile,Chevallier Jessica^ORCID,Pierre Philippe^ORCID,Argüello Rafael J.^ORCID,Spinelli Lionel,Irla Magali^ORCID

Funder

Agence Nationale de la Recherche

Fondation ARC pour la Recherche sur le Cancer

Inserm CoPoC - proof of concept

Publisher

Springer Science and Business Media LLC

Link

https://www.nature.com/articles/s41467-024-51164-5.pdf

Reference77 articles.

1. Fontenot, J. D., Dooley, J. L., Farr, A. G. & Rudensky, A. Y. Developmental regulation of Foxp3 expression during ontogeny. J. Exp. Med. 202, 901–906 (2005).

2. Aschenbrenner, K. et al. Selection of Foxp3+ regulatory T cells specific for self antigen expressed and presented by Aire+ medullary thymic epithelial cells. Nat. Immunol. 8, 351–358 (2007).

3. Perry, J. S. A. et al. Distinct contributions of Aire and antigen-presenting-cell subsets to the generation of self-tolerance in the thymus. Immunity 41, 414–426 (2014).

4. Charaix, J. et al. Recirculating Foxp3+ regulatory T cells are restimulated in the thymus under Aire control. Cell. Mol. Life Sci. 79, 355 (2022).

5. Lio, C. W. J. & Hsieh, C. S. A two-step process for thymic regulatory T cell development. Immunity 28, 100–111 (2008).

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