Lymphoid TCF1+CD39+CD8+ T cells maintain stem-like features and contribute to viral control
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Publisher
Springer Science and Business Media LLC
Link
https://www.nature.com/articles/s41590-024-01889-8.pdf
Reference4 articles.
1. Baessler, A. & Vignali, D. T cell exhaustion. Annu. Rev. Immunol. 42, 179–206 (2024). This review comprehensively summarizes CD8+ T cell exhaustion and the stem-like to exhausted CD8+ T cell landscape.
2. Gupta, P. et al. CD39 expression identifies terminally exhausted CD8+ T cells. PLoS Pathog. 11, 10 (2015). This paper reports CD39 as a marker of terminal differentiation and exhaustion in CD8+ T cells in multiple chronic diseases.
3. Nguyen, S. et al. CD8+ T cells in lymphoid tissues exhibit distinct functional and transcriptional signatures that associate with elite control of HIV. Sci. Transl. Med. 11, 523 (2019). This paper demonstrates that non-cytolytic CD8+ T cells in lymph nodes from HIV elite controllers are distinct and suppress viral replication.
4. Nguyen, S. et al. Jigsaw falling into place: A review and perspective of lymphoid tissue CD8+ T cells and control of HIV. Mol. Immunol. 124, 42–50 (2020). This review provides an overview of studies that have focused on differences between peripheral and lymphoid CD8+ T cells in HIV infection.
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