Heme drives hemolysis-induced susceptibility to infection via disruption of phagocyte functions
Author:
Publisher
Springer Science and Business Media LLC
Subject
Immunology,Immunology and Allergy
Link
http://www.nature.com/articles/ni.3590.pdf
Reference77 articles.
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2. World Health Organization. World Malaria Report 2013. World Health Organization: Geneva, 2013.
3. Adamzik, M. et al. Free hemoglobin concentration in severe sepsis: methods of measurement and prediction of outcome. Crit. Care 16, R125 (2012).
4. Larsen, R. et al. A central role for free heme in the pathogenesis of severe sepsis. Sci. Transl. Med. 2, 51ra71 (2010).
5. Schaer, D.J., Buehler, P.W., Alayash, A.I., Belcher, J.D. & Vercellotti, G.M. Hemolysis and free hemoglobin revisited: exploring hemoglobin and hemin scavengers as a novel class of therapeutic proteins. Blood 121, 1276–1284 (2013).
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