Blood pressure polygenic risk scores tackle hard endpoints
Author:
Publisher
Springer Science and Business Media LLC
Link
https://www.nature.com/articles/s41440-024-01876-4.pdf
Reference8 articles.
1. Keaton JM, Kamali Z, Xie T, Vaez A, Williams A, Goleva SB, et al. Genome-wide analysis in over 1 million individuals of European ancestry yields improved polygenic risk scores for blood pressure traits. Nat Genet. 2024;56:778–91.
2. Øvretveit K, Ingeström EML, Spitieris M, Tragante V, Wade KH, Thomas LF, et al. Polygenic risk scores associate with blood pressure traits across the lifespan. Eur J Prev Cardiol. 2024;31:644–54.
3. Kurniansyah N, Goodman MO, Kelly TN, Elfassy T, Wiggins KL, Bis JC, et al. A multi-ethnic polygenic risk score is associated with hypertension prevalence and progression throughout adulthood. Nat Commun. 2022;13:3549.
4. Lambert SA, Abraham G, Inouye M. Towards clinical utility of polygenic risk scores. Hum Mol Genet. 2019;28:R133–R142.
5. Sakaue S, Kanai M, Karjalainen J, Akiyama M, Kurki M, Matoba N, et al. Trans-biobank analysis with 676,000 individuals elucidates the association of polygenic risk scores of complex traits with human lifespan. Nat Med. 2020;26:542–8.
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