Novel chimeric gene promoters responsive to hypoxia and ionizing radiation-Reference-Cited by-同舟云学术

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Novel chimeric gene promoters responsive to hypoxia and ionizing radiation

Published:2002-10 Issue:20 Volume:9 Page:1403-1411
ISSN:0969-7128
Container-title:Gene Therapy
language:en
Short-container-title:Gene Ther

Author:

Greco O,Marples B,Dachs G U,Williams K J,Patterson A V,Scott S D

Publisher

Springer Science and Business Media LLC

Subject

Genetics,Molecular Biology,Molecular Medicine

Link

http://www.nature.com/articles/3301823.pdf

Reference52 articles.

1. Brown JM, Giaccia AJ . The unique physiology of solid tumors: opportunities (and problems) for cancer therapy Cancer Res 1998 58: 1408–1416

2. Dachs GU et al. Targeting gene expression to hypoxic tumor cells Nat Med 1997 3: 515–520

3. Ratcliffe PJ, O'Rourke JF, Maxwell PH, Pugh CW . Oxygen sensing, hypoxia-inducible factor-1 and the regulation of mammalian gene expression J Exp Biol 1998 201: 1153–1162

4. Semenza GL, Wang GL . A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation Mol Cell Biol 1992 12: 5447–5454

5. Wang GL, Jiang BH, Rue EA, Semenza GL . Hypoxia-inducible factor 1 is a basic helix-loop-helix-PAS heterodimer regulated by cellular O2 tension Proc Natl Acad Sci USA 1995 92: 5510–5514

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