Adenovector-mediated gene delivery of interleukin-2 in metastatic breast cancer and melanoma: results of a phase 1 clinical trial

Author:

Stewart A K,Lassam N J,Quirt I C,Bailey D J,Rotstein L E,Krajden M,Dessureault S,Gallinger S,Cappe D,Wan Y,Addison C L,Moen R C,Gauldie J,Graham F L

Publisher

Springer Science and Business Media LLC

Subject

Genetics,Molecular Biology,Molecular Medicine

Reference34 articles.

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2. Zhai Y et al. Antigen-specific tumor vaccines. Development and characterization of recombinant adenoviruses encoding MART1 or gp100 for cancer therapy J Immunol 1996 156: 700–710

3. Stewart AK et al. A phase I study of adenovirus-mediated gene transfer of interleukin 2 cDNA into metastatic breast cancer or melanoma Hum Gene Ther 1997 8: 1403–1414

4. Toloza EM et al. In vivo cancer gene therapy with a recombinant interleukin-2 adenovirus vector Cancer Gene Ther 1996 3: 11–17

5. Sewell DA et al. Safety of in vivo adenovirus-mediated thymidine kinase treatment of oral cancer Arch Otolaryngol Head Neck Surg 1997 123: 1298–1302

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