Molecular spectrum of KRAS, NRAS, BRAF and PIK3CA mutations in Chinese colorectal cancer patients: analysis of 1,110 cases-Reference-Cited by-同舟云学术

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Molecular spectrum of KRAS, NRAS, BRAF and PIK3CA mutations in Chinese colorectal cancer patients: analysis of 1,110 cases

Published:2015-12 Issue:1 Volume:5 Page:
ISSN:2045-2322
Container-title:Scientific Reports
language:en
Short-container-title:Sci Rep

Author:

Zhang Jing,Zheng Jianming,Yang Yinghong,Lu Junliang,Gao Jie,Lu Tao,Sun Jian,Jiang Hui,Zhu Yan,Zheng Yuhui,Liang Zhiyong,Liu Tonghua

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/srep18678.pdf

Reference48 articles.

1. Zheng, Z. X., Zheng, R. S., Zhang, S. W. & Chen, W. Q. Colorectal cancer incidence and mortality in china, 2010. Asian Pac J Cancer Prev 15, 8455–8460 (2014 ).

2. Arnold, D. & Schmoll, H. J. Colorectal cancer: (neo-) adjuvant treatments in colorectal cancer. Ann Oncol 16, 133–140 (2005).

3. Engelman, J. A. Targeting PI3K signalling in cancer: opportunities, challenges and limitations. Nat Rev Cancer 9, 550–562 (2009).

4. Samuels, Y. et al. Mutant PIK3CA promotes cell growth and invasion of human cancer cells. Cancer Cell 7, 561–573 (2005).

5. McCubrey, J. A. et al. Roles of the RAF/MEK/ERK and PI3K/PTEN/AKT pathways in malignant transformation and drug resistance. Adv Enzyme Regul 46, 249–279 (2006).

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