Akt mediates mitochondrial protection in cardiomyocytes through phosphorylation of mitochondrial hexokinase-II
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology,Molecular Biology
Link
http://www.nature.com/articles/4402285.pdf
Reference40 articles.
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3. Matsui T, Li L, del Monte F, Fukui Y, Franke TF, Hajjar RJ et al. Adenoviral gene transfer of activated phosphatidylinositol 3′-kinase and Akt inhibits apoptosis of hypoxic cardiomyocytes in vitro. Circulation 1999; 100: 2373–2379.
4. Fujio Y, Nguyen T, Wencker D, Kitsis RN, Walsh K . Akt promotes survival of cardiomyocytes in vitro and protects against ischemia-reperfusion injury in mouse heart. Circulation 2000; 101: 660–667.
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