Author:
Waditee-Sirisattha Rungaroon,Ito Hiroshi,Kageyama Hakuto
Abstract
AbstractSubstantial evidence has been accumulated about the molecular basis underlying halotolerance; however, insights into the regulatory networks for relevant genes and mechanisms of their interplay remain elusive. Here, we present a comprehensive transcriptome investigation, using RNA sequencing, of specific metabolic pathways and networks in a halotolerant cyanobacterium, Halothece sp. PCC7418, including the circadian rhythm profile. Dissecting the transcriptome presented the intracellular regulation of gene expressions, which was linked with ion homeostasis, protein homeostasis, biosynthesis of compatible solutes, and signal transduction, for adaptations to high-salinity environments. The efficient production and distribution of energy were also implicated in this acclimation process. Furthermore, we found that high-salinity environments had a dramatic effect on the global transcriptional expression regulated by the circadian clock. Our findings can provide a comprehensive transcriptome for elucidating the molecular mechanisms underlying halotolerance in cyanobacteria.
Funder
Thailand Science Research and Innovation Fund
Japan Society for the Promotion of Science
Mayekawa Houonkai Foundation
the Research Institute of Meijo University
Publisher
Springer Science and Business Media LLC
Cited by
3 articles.
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