Insulin-degrading enzyme is not secreted from cultured cells
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-018-20597-6.pdf
Reference39 articles.
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2. Leissring, M. A. et al. Alternative translation initiation generates a novel isoform of insulin-degrading enzyme targeted to mitochondria. Biochemical Journal 383, 439–446, https://doi.org/10.1042/BJ20041081 (2004).
3. Morita, M. et al. Insulin-degrading enzyme exists inside of rat liver peroxisomes and degrades oxidized proteins. Cell. Struct. Funct. 25, 309–315 (2000).
4. Hamel, F. G., Mahoney, M. J. & Duckworth, W. C. Degradation of intraendosomal insulin by insulin-degrading enzyme without acidification. Diabetes 40, 436–443 (1991).
5. Fernandez-Gamba, A., Leal, M. C., Morelli, L. & Castano, E. M. Insulin-degrading enzyme: structure-function relationship and its possible roles in health and disease. Curr. Pharm. Des. 15, 3644–3655 (2009).
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