A bacterial metabolite ameliorates periodontal pathogen-induced gingival epithelial barrier disruption via GPR40 signaling
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-018-27408-y.pdf
Reference62 articles.
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3. Sharon, G. et al. Specialized metabolites from the microbiome in health and disease. Cell Metab 20, 719–730, https://doi.org/10.1016/j.cmet.2014.10.016 (2014).
4. Kishino, S. et al. Polyunsaturated fatty acid saturation by gut lactic acid bacteria affecting host lipid composition. Proc. Natl. Acad. Sci. USA 110, 17808–17813, https://doi.org/10.1073/pnas.1312937110 (2013).
5. Goto, T. et al. 10-oxo-12(Z)-octadecenoic acid, a linoleic acid metabolite produced by gut lactic acid bacteria, potently activates PPARgamma and stimulates adipogenesis. Biochem. Biophys. Res. Commun. 459, 597–603, https://doi.org/10.1016/j.bbrc.2015.02.154 (2015).
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