Dual β-lactam combination therapy for multi-drug resistant Pseudomonas aeruginosa infection: enhanced efficacy in vivo and comparison with monotherapies of penicillin-binding protein inhibition
Author:
Funder
Thailand Research Fund
University of St Andrews
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-019-45550-z.pdf
Reference53 articles.
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2. Palavutitotai, N., Jitmuang, A., Tongsai, S., Kiratisin, P. & Angkasekwinai, N. Epidemiology and risk factors of extensively drug-resistant Pseudomonas aeruginosa infections. PLoS One. 13, https://doi.org/10.1371/journal.pone.0193431 (2018).
3. Castanheira, M., Mills, J. C., Farrell, D. J. & Jones, R. N. Mutation-driven beta-lactam resistance mechanisms among contemporary ceftazidime-nonsusceptible Pseudomonas aeruginosa isolates from U.S. hospitals. Antimicrob. Agents Chemother. 58, 6844–50 (2014).
4. Laudy, A.E., Osinska, P., Nanyslowska, A., Zajac, O. & Tyski, S. Modification of the susceptibility of Gram-negative rods producing ESBLs to beta-lactams by the efflux pump phenomenon. PLoS One. 10, https://doi.org/10.1371/journal.pone.0119997 (2015).
5. Ramirez, D. G. et al. Emergence of Pseudomonas aeruginosa with KPC-type carbapenemase in a teaching hospital: an 8-year study. J. Med. Microbiol. 62, 1565–70 (2013).
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