Decoy peptide targeted to Toll-IL-1R domain inhibits LPS and TLR4-active metabolite morphine-3 glucuronide sensitization of sensory neurons
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-017-03447-9.pdf
Reference60 articles.
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2. Wadachi, R. & Hargreaves, K. M. Trigeminal nociceptors express TLR-4 and CD14: a mechanism for pain due to infection. J Dent Res 85, 49–53, doi: 10.1177/154405910608500108 (2006).
3. Ochoa-Cortes, F. et al. Bacterial cell products signal to mouse colonic nociceptive dorsal root ganglia neurons. Am J Physiol Gastrointest Liver Physiol 299, G723–732, doi: 10.1152/ajpgi.00494.2009 (2010).
4. Due, M. R. et al. Neuroexcitatory effects of morphine-3-glucuronide are dependent on Toll-like receptor 4 signaling. J Neuroinflammation 9, 200, doi: 10.1186/1742-2094-9-200 (2012).
5. Due, M. R. et al. Carbamazepine potentiates the effectiveness of morphine in a rodent model of neuropathic pain. PLoS One 9, e107399, doi: 10.1371/journal.pone.0107399 (2014).
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