Neuroexcitatory effects of morphine-3-glucuronide are dependent on Toll-like receptor 4 signaling-Reference-Cited by-同舟云学术

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Neuroexcitatory effects of morphine-3-glucuronide are dependent on Toll-like receptor 4 signaling

Published:2012-08-16 Issue:1 Volume:9 Page:
ISSN:1742-2094
Container-title:Journal of Neuroinflammation
language:en
Short-container-title:J Neuroinflammation

Author:

Due Michael R,Piekarz Andrew D,Wilson Natalie,Feldman Polina,Ripsch Matthew S,Chavez Sherry,Yin Hang,Khanna Rajesh,White Fletcher A

Publisher

Springer Science and Business Media LLC

Subject

Cellular and Molecular Neuroscience,Neurology,Immunology,General Neuroscience

Link

http://link.springer.com/content/pdf/10.1186/1742-2094-9-200.pdf

Reference46 articles.

1. Coughtrie MW, Ask B, Rane A, Burchell B, Hume R: The enantioselective glucuronidation of morphine in rats and humans. Evidence for the involvement of more than one UDP-glucuronosyltransferase isoenzyme. Biochem Pharmacol 1989, 38:3273–3280.

2. Zelcer N, van de Wetering K, Hillebrand M, Sarton E, Kuil A, Wielinga PR, Tephly T, Dahan A, Beijnen JH, Borst P: Mice lacking multidrug resistance protein 3 show altered morphine pharmacokinetics and morphine-6-glucuronide antinociception. Proc Natl Acad Sci U S A 2005, 102:7274–7279.

3. Osborne R, Joel S, Trew D, Slevin M: Morphine and metabolite behavior after different routes of morphine administration: demonstration of the importance of the active metabolite morphine-6-glucuronide. Clin Pharmacol Ther 1990, 47:12–19.

4. Hasselstrom J, Sawe J: Morphine pharmacokinetics and metabolism in humans. Enterohepatic cycling and relative contribution of metabolites to active opioid concentrations. Clin Pharmacokinet 1993, 24:344–354.

5. van Dorp EL, Romberg R, Sarton E, Bovill JG, Dahan A: Morphine-6-glucuronide: morphine’s successor for postoperative pain relief? Anesth Analg 2006, 102:1789–1797.

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