Allosteric inhibition of the guanine nucleotide exchange factor DOCK5 by a small molecule
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-017-13619-2.pdf
Reference42 articles.
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3. Laurin, M. & Cote, J. F. Insights into the biological functions of Dock family guanine nucleotide exchange factors. Genes Dev 28, 533–547, https://doi.org/10.1101/gad.236349.113 (2014).
4. Yang, J., Zhang, Z., Roe, S. M., Marshall, C. J. & Barford, D. Activation of Rho GTPases by DOCK exchange factors is mediated by a nucleotide sensor. Science 325, 1398–1402, https://doi.org/10.1126/science.1174468 (2009).
5. Kulkarni, K., Yang, J., Zhang, Z. & Barford, D. Multiple factors confer specific Cdc42 and Rac protein activation by dedicator of cytokinesis (DOCK) nucleotide exchange factors. J Biol Chem 286, 25341–25351, https://doi.org/10.1074/jbc.M111.236455 (2011).
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