Opioid receptor signaling, analgesic and side effects induced by a computationally designed pH-dependent agonist-Reference-Cited by-同舟云学术

Opioid receptor signaling, analgesic and side effects induced by a computationally designed pH-dependent agonist

Published:2018-06-12 Issue:1 Volume:8 Page:
ISSN:2045-2322
Container-title:Scientific Reports
language:en
Short-container-title:Sci Rep

Author:

Spahn Viola^ORCID,Del Vecchio Giovanna^ORCID,Rodriguez-Gaztelumendi Antonio,Temp Julia^ORCID,Labuz Dominika,Kloner Michael,Reidelbach Marco,Machelska Halina,Weber Marcus,Stein Christoph^ORCID

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/s41598-018-27313-4.pdf

Reference35 articles.

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2. Del Vecchio, G., Spahn, V. & Stein, C. Novel Opioid Analgesics and Side Effects. ACS Chem Neurosci 8, 1638–1640 (2017).

3. Stein, C. Opioid Receptors. Annu Rev Med 67, 433–451 (2016).

4. Stein, C. & Machelska, H. Modulation of peripheral sensory neurons by the immune system: implications for pain therapy. Pharmacol Rev 63, 860–881 (2011).

5. Spahn, V. et al. A nontoxic pain killer designed by modeling of pathological receptor conformations. Science 355, 966–969 (2017).

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