The E3 SUMO ligase PIASγ is a novel interaction partner regulating the activity of diabetes associated hepatocyte nuclear factor-1α
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-018-29448-w.pdf
Reference57 articles.
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2. Mitchell, S. M. & Frayling, T. M. The role of transcription factors in maturity-onset diabetes of the young. Molecular genetics and metabolism 77, 35–43 (2002).
3. Shih, D. Q. et al. Loss of HNF-1α Function in Mice Leads to Abnormal Expression of Genes Involved in Pancreatic Islet Development and Metabolism. Diabetes 50, 2472–2480, https://doi.org/10.2337/diabetes.50.11.2472 (2001).
4. Colclough, K., Bellanne-Chantelot, C., Saint-Martin, C., Flanagan, S. E. & Ellard, S. Mutations in the genes encoding the transcription factors hepatocyte nuclear factor 1 alpha and 4 alpha in maturity-onset diabetes of the young and hyperinsulinemic hypoglycemia. Human mutation 34, 669–685, https://doi.org/10.1002/humu.22279 (2013).
5. Yamagata, K. et al. Mutations in the hepatocyte nuclear factor-1alpha gene in maturity-onset diabetes of the young (MODY3). Nature 384, 455–458, https://doi.org/10.1038/384455a0 (1996).
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