Author:
Lee Min-Woo,Kim Tae-Yeon,Song Yong-Yeon,Baek Seung-Kook,Lee Young-Hoon
Abstract
AbstractTo analyze the changes in each retinal layer and the recovery of the ellipsoid zone (EZ) after full-thickness macular hole (FTMH) surgery. Patients who underwent surgery for FTMH were included. Spectral-domain optical coherence tomography (SD-OCT) was performed preoperatively and postoperatively at 1, 3, 6, 9, and 12 months. A total of 32 eyes were enrolled. Ganglion cell layer, inner plexiform layer, and inner nuclear layer showed significant reductions over time after surgery (P = 0.020, P = 0.001, and P = 0.001, respectively), but were significantly thicker than those of fellow eyes at 12 months postoperatively. The average recovery duration of the external limiting membrane (ELM), outer nuclear layer (ONL), and EZ was 1.5, 2.1, and 6.1 months, respectively. Baseline best-corrected visual acuity (BCVA) (P = 0.003), minimum linear diameter (MLD) (P = 0.025), recovery of EZ (P = 0.008), and IRL thickness (P < 0.001) were significant factors associated with changes in the BCVA. Additionally, axial length (P < 0.001), MLD (P = 0.020), and IRL thickness (P = 0.001) showed significant results associated with EZ recovery. The IRL gradually became thinner after FTMH surgery but was still thicker than that of the fellow eye at 12 months postoperatively. The recovery of ELM and ONL may be a prerequisite for the EZ recovery. The BCVA change was affected by baseline BCVA, MLD, recovery of EZ, and IRL thickness. Additionally, axial length, MLD, and IRL thickness were significantly associated with EZ recovery.
Publisher
Springer Science and Business Media LLC
Reference25 articles.
1. Ch’ng, S. W. et al. The manchester large macular hole study: Is it time to reclassify large macular holes?. Am. J. Ophthalmol. 195, 36–42 (2018).
2. Krishnan, R., Tossounis, C. & Yang, Y. F. 20-gauge and 23-gauge phacovitrectomy for idiopathic macular holes: Comparison of complications and long-term outcomes. Eye 27, 72–77 (2013).
3. Passemard, M. et al. Long-term outcome of idiopathic macular hole surgery. Am. J. Ophthalmol. 149, 120–126 (2010).
4. Michalewska, Z., Michalewski, J., Adelman, R. A. & Nawrocki, J. Inverted internal limiting membrane flap technique for large macular holes. Ophthalmology 117, 2018–2025 (2010).
5. Moysidis, S. N. et al. Autologous retinal transplantation for primary and refractory macular holes and macular hole retinal detachments: The global consortium. Ophthalmology 2, 2 (2020).
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