Nuclear accumulation of symplekin promotes cellular proliferation and dedifferentiation in an ERK1/2-dependent manner
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-017-04005-z.pdf
Reference50 articles.
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2. Kavanagh, E. et al. Functional interaction between the ZO-1-interacting transcription factor ZONAB/DbpA and the RNA processing factor symplekin. J. Cell Sci. 119, 5098–5105 (2006).
3. Buchert, M. et al. The symplekin/ZONAB complex inhibits intestinal cell differentiation by the repression of AML1/Runx1. Gastroenterology 137, 156–164. e153 (2009).
4. Cappell, K. M., Larson, B., Sciaky, N. & Whitehurst, A. W. Symplekin specifies mitotic fidelity by supporting microtubule dynamics. Mol. Cell. Biol. 30, 5135–5144 (2010).
5. Buchert, M. et al. Symplekin promotes tumorigenicity by up-regulating claudin-2 expression. Proc. Natl. Acad. Sci. USA 107, 2628–2633 (2010).
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