Author:
Khokhlova Anna,Zolotovskii Igor,Sokolovski Sergei,Saenko Yury,Rafailov Edik,Stoliarov Dmitrii,Pogodina Evgenia,Svetukhin Vyacheslav,Sibirny Vladimir,Fotiadi Andrei
Abstract
AbstractHere at the first time we suggested that the surface plasmon-polariton phenomenon which it is well described in metallic nanostructures could also be used for explanation of the unexpectedly strong oxidative effects of the low-intensity laser irradiation in living matters (cells, tissues, organism). We demonstrated that the narrow-band laser emitting at 1265 nm could generate significant amount of the reactive oxygen species (ROS) in both HCT116 and CHO-K1 cell cultures. Such cellular ROS effects could be explained through the generation of highly localized plasmon-polaritons on the surface of mitochondrial crista. Our experimental conditions, the low-intensity irradiation, the narrow spectrum band (<4 nm) of the laser and comparably small size bio-structures (~10 μm) were shown to be sufficient for the plasmon-polariton generation and strong laser field confinement enabling the oxidative stress observed.
Funder
Российский Фонд Фунд Исследований
Russian Science Foundation
H2020 Future and Emerging Technologies
Publisher
Springer Science and Business Media LLC
Cited by
15 articles.
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