Cytotoxicity of eupatorin in MCF-7 and MDA-MB-231 human breast cancer cells via cell cycle arrest, anti-angiogenesis and induction of apoptosis
Author:
Funder
Fundamental Research Grant Scheme (NFHD0002) from Ministry of Higher Education, Malaysia
Mardi internal fund
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-018-37796-w.pdf
Reference51 articles.
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3. La porta, E. & Welsh, J. Modelling vitamin D in triple negative/basal likebreast cancer-Review. J. Steroid Biochem. Mol. Bio. 144, 65–73 (2014).
4. Androutsopoulos, V. P. & Tsatsakis, A. M. Benzo[a]pyrene sensitizes MCF7 breast cancer cells to induction of G1 arrest by the natural flavonoid eupatorin-5-methyl ether, via activation of cell signaling proteins and CYP1-mediated metabolism. Toxicol. Lett. 230, 304–313 (2013).
5. Park, E. J. et al. Down-regulation of c-Src/EGFR-mediated signaling activation is involved in the honokiol-induced cell cycle arrest and apoptosis in MDA-MB-231 human breast cancer cells. Cancer Lett. 277, 133–140 (2009).
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