Glutamine 89 is a key residue in the allosteric modulation of human serine racemase activity by ATP-Reference-Cited by-同舟云学术

Glutamine 89 is a key residue in the allosteric modulation of human serine racemase activity by ATP

Published:2018-06-13 Issue:1 Volume:8 Page:
ISSN:2045-2322
Container-title:Scientific Reports
language:en
Short-container-title:Sci Rep

Author:

Canosa Andrea V.,Faggiano Serena,Marchetti Marialaura,Armao Stefano,Bettati Stefano^ORCID,Bruno Stefano,Percudani Riccardo^ORCID,Campanini Barbara^ORCID,Mozzarelli Andrea

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/s41598-018-27227-1.pdf

Reference54 articles.

1. Mothet, J. P. et al. D-serine is an endogenous ligand for the glycine site of the N-methyl-D-aspartate receptor. Proc. Natl. Acad. Sci. USA 97, 4926–4931, https://doi.org/10.1073/pnas.97.9.4926 (2000).

2. Cook, S. P., Galve-Roperh, I., del Pozo, A. M. & Rodriguez-Crespo, I. Direct calcium binding results in activation of brain serine racemase. J. Biol. Chem. 277, 27782–27792, https://doi.org/10.1074/jbc.M111814200 (2002).

3. de Miranda, J., Panizzutti, R., Foltyn, V. N. & Wolosker, H. Cofactors of serine racemase that physiologically stimulate the synthesis of the N-methyl-D-aspartate (NMDA) receptor coagonist D-serine. Proc. Natl. Acad. Sci. USA 99, 14542–14547, https://doi.org/10.1073/pnas.222421299 (2002).

4. De Miranda, J., Santoro, A., Engelender, S. & Wolosker, H. Human serine racemase: moleular cloning, genomic organization and functional analysis. Gene 256, 183–188, https://doi.org/10.1016/s0378-1119(00)00356-5 (2000).

5. Foltyn, V. N. et al. Serine racemase modulates intracellular D-serine levels through an alpha,beta-elimination activity. J. Biol. Chem. 280, 1754–1763, https://doi.org/10.1074/jbc.M405726200 (2005).

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