Information-Rich, Dual-Function 13C/2H-Isotopic Crosstalk NMR Assay for Human Serine Racemase (hSR) Provides a PLP-Enzyme “Partitioning Fingerprint” and Reveals Disparate Chemotypes for hSR Inhibition

Author:

Ramos de Dios Stephany M.1ORCID,Hass Jared L.1ORCID,Graham Danielle L.1ORCID,Kumar Nivesh1ORCID,Antony Aina E.1ORCID,Morton Martha D.1ORCID,Berkowitz David B.1ORCID

Affiliation:

1. Department of Chemistry, University of Nebraska, Lincoln, Lincoln, Nebraska 68588, United States

Funder

Cambridge Isotope Laboratories

Division of Chemical, Bioengineering, Environmental, and Transport Systems

University of Nebraska-Lincoln, College of Arts and Sciences

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

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