Second messenger analogues highlight unexpected substrate sensitivity of CD38: total synthesis of the hybrid “L-cyclic inosine 5′-diphosphate ribose”
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-017-16388-0.pdf
Reference50 articles.
1. Howard, M. et al. Formation and hydrolysis of cyclic ADP-ribose catalyzed by lymphocyte antigen CD38. Science 262, 1056–1059 (1993).
2. Partida-Sanchez, S. et al. Chemotaxis of mouse bone marrow neutrophils and dendritic cells is controlled by adp-ribose, the major product generated by the CD38 enzyme reaction. J. Immunol. 179, 7827–7839 (2007).
3. Cosker, F. et al. The ecto-enzyme CD38 is a nicotinic acid adenine dinucleotide phosphate (NAADP) synthase that couples receptor activation to Ca2+ mobilization from lysosomes in pancreatic acinar cells. J. Biol. Chem. 285, 38251–38259 (2010).
4. Zhao, Y. J., Lam, C. M. C. & Lee, H. C. The Membrane-Bound Enzyme CD38 Exists in Two Opposing Orientations. Sci. Signal. 5, ra67 (2012).
5. Fliegert, R. et al. 2′-Deoxyadenosine 5′-diphosphoribose is an endogenous TRPM2 agonist. Nat. Chem. Biol., 13, 1036-1044 (2017).
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