2′-Deoxyadenosine 5′-diphosphoribose is an endogenous TRPM2 superagonist
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology,Molecular Biology
Link
http://www.nature.com/articles/nchembio.2415.pdf
Reference50 articles.
1. Perraud, A.L. et al. ADP-ribose gating of the calcium-permeable LTRPC2 channel revealed by Nudix motif homology. Nature 411, 595–599 (2001).
2. Knowles, H., Li, Y. & Perraud, A.L. The TRPM2 ion channel, an oxidative stress and metabolic sensor regulating innate immunity and inflammation. Immunol. Res. 55, 241–248 (2013).
3. Faouzi, M. & Penner, R. in Mammalian Transient Receptor Potential (TRP) Cation Channels Vol. 222 (eds. Nilius, B. & Flockerzi, V.) 403–426 (Springer, 2014).
4. Gasser, A. et al. Activation of T cell calcium influx by the second messenger ADP-ribose. J. Biol. Chem. 281, 2489–2496 (2006).
5. Buelow, B., Song, Y. & Scharenberg, A.M. The Poly(ADP-ribose) polymerase PARP-1 is required for oxidative stress-induced TRPM2 activation in lymphocytes. J. Biol. Chem. 283, 24571–24583 (2008).
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