NNMT activation can contribute to the development of fatty liver disease by modulating the NAD + metabolism-Reference-Cited by-同舟云学术

NNMT activation can contribute to the development of fatty liver disease by modulating the NAD + metabolism

Published:2018-06-05 Issue:1 Volume:8 Page:
ISSN:2045-2322
Container-title:Scientific Reports
language:en
Short-container-title:Sci Rep

Author:

Komatsu Motoaki,Kanda Takeshi,Urai Hidenori,Kurokochi Arata,Kitahama Rina,Shigaki Shuhei,Ono Takashi,Yukioka Hideo,Hasegawa Kazuhiro,Tokuyama Hirobumi,Kawabe Hiroshi,Wakino Shu,Itoh Hiroshi

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/s41598-018-26882-8.pdf

Reference51 articles.

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2. Angulo, P. Nonalcoholic fatty liver disease. The New England journal of medicine 346, 1221–1231, https://doi.org/10.1056/NEJMra011775 (2002).

3. Canto, C., Menzies, K. J. & Auwerx, J. NAD(+) Metabolism and the Control of Energy Homeostasis: A Balancing Act between Mitochondria and the Nucleus. Cell metabolism 22, 31–53, https://doi.org/10.1016/j.cmet.2015.05.023 (2015).

4. Gariani, K. et al. Eliciting the mitochondrial unfolded protein response by nicotinamide adenine dinucleotide repletion reverses fatty liver disease in mice. Hepatology (Baltimore, Md.) 63, 1190–1204, https://doi.org/10.1002/hep.28245 (2016).

5. Ganji, S. H., Kukes, G. D., Lambrecht, N., Kashyap, M. L. & Kamanna, V. S. Therapeutic role of niacin in the prevention and regression of hepatic steatosis in rat model of nonalcoholic fatty liver disease. American journal of physiology. Gastrointestinal and liver physiology 306, G320–327, https://doi.org/10.1152/ajpgi.00181.2013 (2014).

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