Large-scale in-silico statistical mutagenesis analysis sheds light on the deleteriousness landscape of the human proteome
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-018-34959-7.pdf
Reference58 articles.
1. Lek, M. et al. Analysis of protein-coding genetic variation in 60,706 humans. Nature 536(7616), 285 (2016).
2. Pabinger, S. et al. A survey of tools for variant analysis of next-generation genome sequencing data. Briefings in bioinformatics 15(2), 256–278 (2014).
3. Van Dijk, E. L., Auger, H., Jaszczyszyn, Y. & Thermes, C. Ten years of next-generation sequencing technology. Trends in genetics 30(9), 418–426 (2014).
4. Rabbani, B., Tekin, M. & Mahdieh, N. The promise of whole-exome sequencing in medical genetics. Journal of human genetics 59(1), 5 (2014).
5. Adzhubei, I. A. et al. A method and server for predicting damaging missense mutations. Nature methods 7(4), 248 (2010).
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