Probing Resistance Mutations in Retroviral Integrases by Direct Measurement of Dolutegravir Fluorescence
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-017-14564-w.pdf
Reference51 articles.
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2. Lusic, M. & Siliciano, R. F. Nuclear landscape of HIV-1 infection and integration. Nat. Rev. Microbiol. 15, 69–82 (2017).
3. Neamati, N. HIV-1 integrase: Mechanism and inhibitor design, Wiley series on drug discovery and development, Wiley & Sons: New York (2011).
4. Engelman, A. & Cherepanov, P. The structural biology of HIV-1: mechanistic and therapeutic insights. Nat. Rev. Microbiol. 10, 279–290 (2012).
5. Hazuda, D. J. et al. Inhibitors of strand transfer that prevent integration and inhibit HIV-1 replication in cells. Science 287, 646–650 (2000).
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