In vivo-like 3-D model for sodium nitrite- and acrylamide-induced hepatotoxicity tests utilizing HepG2 cells entrapped in micro-hollow fibers
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-017-13147-z.pdf
Reference42 articles.
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3. Li, A. P. Accurate prediction of human drug toxicity: a major challenge in drug development. Chemico-biological interactions 150(1), 3–7 (2004).
4. Ichihara, A., Nakamura, T. & Tanaka, K. Use of hepatocytes in primary culture for biochemical studies on liver functions. Molecular and cellular Biochemistry 43(3), 145–160 (1982).
5. Holme, J. A. Xenobiotic metabolism and toxicity in primary monolayer cultures of hepatocytes. NIPH annals 8(2), 49–63 (1985).
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