Accurate prediction of human drug toxicity: a major challenge in drug development
Author:
Publisher
Elsevier BV
Subject
Toxicology,General Medicine
Reference7 articles.
1. Timing of new black box warnings and withdrawals for prescription medications;Lasser;J. Am. Med. Assoc.,2002
2. The price of innovation: new estimates of drug development costs;Dimasi;J. Health Econ.,2003
3. The value of improving the productivity of the drug development process: faster times and better decisions;DiMasi;Pharmacoeconomics,2002
4. A comparison of aroclor 1254-induced and uninduced rat liver microsomes to human liver microsomes in phenytoin O-deethylation, coumarin 7-hydroxylation, tolbutamide 4-hydroxylation, S-mephenytoin 4′-hydroxylation, chloroxazone 6-hydroxylation and testosterone 6β-hydroxylation
5. Myelotoxic effects of the bifunctional alkylating agent bizelesin on human, canine and murine myeloid progenitor cells;Volpe;Cancer Chemother. Pharmacol.,1996
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