The de novo design of a biocompatible and functional integral membrane protein using minimal sequence complexity
Author:
Funder
Biotechnology and Biological Sciences Research Council
EC | European Research Council
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-018-31964-8.pdf
Reference60 articles.
1. Lear, J. D., Wasserman, Z. R. & DeGrado, W. F. Synthetic amphiphilic peptide models for protein ion channels. Science 240, 1177–1181 (1988).
2. Korendovych, I. V. et al. De novo design and molecular assembly of a transmembrane diporphyrin-binding protein complex. J Am Chem Soc 132, 15516–15518 (2010).
3. Joh, N. H. et al. De novo design of a transmembrane Zn2+-transporting four-helix bundle. Science 346, 1520–1524 (2014).
4. Discher, B. M. et al. Design of amphiphillic protein maquettes: controlling assembly, membrane insertion, and cofactor interactions. Biochemistry 44, 12329–12343 (2005).
5. Lu, P. et al. Accurate computational design of multipass transmembrane proteins. Science 359, 1042–1046 (2018).
Cited by 17 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Computational design of de novo bioenergetic membrane proteins;Biochemical Society Transactions;2024-07-03
2. Cellular production of a de novo membrane cytochrome;Proceedings of the National Academy of Sciences;2023-04-10
3. Transforming an esterase into an enantioselective catecholase through bioconjugation of a versatile metal-chelating inhibitor;Chemical Communications;2023
4. Towards de novo design of transmembrane α-helical assemblies using structural modelling and molecular dynamics simulation;Physical Chemistry Chemical Physics;2023
5. Cellular production of ade novomembrane cytochrome;2022-12-06
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3