Towards <i>de novo</i> design of transmembrane α-helical assemblies using structural modelling and molecular dynamics simulation-Reference-Cited by-同舟云学术

Towards de novo design of transmembrane α-helical assemblies using structural modelling and molecular dynamics simulation

Published:2023 Issue:5 Volume:25 Page:3595-3606
ISSN:1463-9076
Container-title:Physical Chemistry Chemical Physics
language:en
Short-container-title:Phys. Chem. Chem. Phys.

Author:

Niitsu Ai¹^ORCID,Sugita Yuji¹²³^ORCID

Affiliation:

1. Theoretical Molecular Science Laboratory, RIKEN Cluster for Pioneering Research, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan

2. Computational Biophysics Research Team, RIKEN Center for Computational Science, 7-1-26 Minatojima-minamimachi, Chuo-ku, Kobe, Hyogo 650-0047, Japan

3. Laboratory for Biomolecular Function Simulation, RIKEN Center for Biosystems Dynamics Research, 6-7-1 Minatojima-minamimachi, Chuo-ku, Kobe, Hyogo 650-0047, Japan

Abstract

This review discusses a potential new approach to de novo design of membrane proteins aided by advanced molecular dynamics simulations.

Funder

Japan Science and Technology Agency

RIKEN

Ministry of Education, Culture, Sports, Science and Technology

Publisher

Royal Society of Chemistry (RSC)

Subject

Physical and Theoretical Chemistry,General Physics and Astronomy

Link

http://pubs.rsc.org/en/content/articlepdf/2023/CP/D2CP03972A