Intramolecular hydroamination catalysed by gold nanoparticles deposited on fibrillated cellulose

Abstract

AbstractGold nanoparticles stabilised by fibrillated citric acid-modified cellulose (Au:F-CAC) catalyse the intramolecular cycloamination of amines to unactivated alkenes under an aerobic atmosphere to afford pyrrolidine derivatives. Only 0.2 mol% of Au loading is required to complete the reaction. The high sensitivity of the Au:F-CAC catalyst to the substitution pattern of alkenes allows a unique chemoselective cycloamination, affording new compounds.