Increased Plasma Levels of the TH2 chemokine CCL18 associated with low CD4+ T cell counts in HIV-1-infected Patients with a Suppressed Viral Load-Reference-Cited by-同舟云学术

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Increased Plasma Levels of the TH2 chemokine CCL18 associated with low CD4+ T cell counts in HIV-1-infected Patients with a Suppressed Viral Load

Published:2019-04-12 Issue:1 Volume:9 Page:
ISSN:2045-2322
Container-title:Scientific Reports
language:en
Short-container-title:Sci Rep

Author:

Malhotra Prashant,Haslett Patrick,Sherry Barbara,Shepp David H.,Barber Paul,Abshier Jonathan,Roy Upal,Schmidtmayerova Helena

Funder

U.S. Department of Health & Human Services | NIH | National Institute of Allergy and Infectious Diseases

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/s41598-019-41588-1.pdf

Reference36 articles.

1. Mohan, M. et al. Focused examination of the intestinal lamina propria yields greater molecular insight into mechanisms underlying SIV induced immune dysfunction. PLoS One. 7(4), e34561, https://doi.org/10.1371/journal.pone.0034561 (2012).

2. Sattentau, Q. J. & Stevenson, M. Macrophages, and HIV-1 – an unhealthy constellation. Cell host & microbe. 19(3), 304–310, https://doi.org/10.1016/j.chom.2016.02.013 (2016).

3. Robinson, T. O., Zhang, M., Ochsenbauer, C., Smythies, L. E. & Cron, R. Q. CD4 regulatory T cells augment HIV-1 expression of polarized M1 and M2 monocyte-derived macrophages. Virology 504, 79–87 (2017).

4. Daftarian, M. P., az-Mitoma, F., Creery, W. D., Cameron, W. & Kumar, A. Dysregulated production of interleukin-10 (IL-10) and IL-12 by peripheral blood lymphocytes from human immunodeficiency virus-infected individuals is associated with altered proliferative responses to recall antigens. Clin Diagn Lab Immunol. 2, 712–718 (1995).

5. Altfeld, M. et al. T(H)1 to T(H)2 shift of cytokines in peripheral blood of HIV-infected patients is detectable by reverse transcriptase polymerase chain reaction but not by enzyme-linked immunosorbent assay under nonstimulated conditions. J Acquir Immune Defic Syndr. 23, 287–294 (2000).

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