High-throughput identification of peptide agonists against GPCRs by co-culture of mammalian reporter cells and peptide-secreting yeast cells using droplet microfluidics
Author:
Funder
MEXT | JST | Core Research for Evolutional Science and Technology
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-019-47388-x.pdf
Reference40 articles.
1. Jacoby, E., Bouhelal, R., Gerspacher, M. & Seuwen, K. The 7 TM G‐protein‐coupled receptor target family. ChemMedChem: Chemistry Enabling Drug Discovery 1, 760–782 (2006).
2. Jaakola, V.-P. et al. The 2.6 angstrom crystal structure of a human A2A adenosine receptor bound to an antagonist. Science 322, 1211–1217 (2008).
3. Chien, E. Y. et al. Structure of the human dopamine D3 receptor in complex with a D2/D3 selective antagonist. Science 330, 1091–1095 (2010).
4. Shimamura, T. et al. Structure of the human histamine H 1 receptor complex with doxepin. Nature 475, 65 (2011).
5. Wacker, D. et al. Structural features for functional selectivity at serotonin receptors. Science 340, 615–619 (2013).
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