Identifying Recrudescent Plasmodium falciparum in Treated Malaria Patients by Real-time PCR and High Resolution Melt Analysis of Genetic Diversity
Author:
Funder
European and Developing Countries Clinical Trials Partnership (EDCTP)
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-018-28179-2.pdf
Reference22 articles.
1. Ashley, E. A. et al. Spread of artemisinin resistance in Plasmodium falciparum malaria. N Engl J Med 371, 411–423, https://doi.org/10.1056/NEJMoa1314981 (2014).
2. Gosi, P. et al. Evaluation of parasite subpopulations and genetic diversity of the msp1, msp2 and glurp genes during and following artesunate monotherapy treatment of Plasmodium falciparum malaria in Western Cambodia. Malar J 12, 403, https://doi.org/10.1186/1475-2875-12-403 (2013).
3. van Schalkwyk, D. A. et al. Culture-adapted Plasmodium falciparum isolates from UK travellers: in vitro drug sensitivity, clonality and drug resistance markers. Malar J 12, 320, https://doi.org/10.1186/1475-2875-12-320 (2013).
4. Henriques, G. et al. Directional selection at the pfmdr1, pfcrt, pfubp1, and pfap2mu loci of Plasmodium falciparum in Kenyan children treated with ACT. J Infect Dis 210, 2001–2008, https://doi.org/10.1093/infdis/jiu358 (2014).
5. Beshir, K. B. et al. Residual Plasmodium falciparum parasitemia in Kenyan children after artemisinin-combination therapy is associated with increased transmission to mosquitoes and parasite recurrence. J Infect Dis 208, 2017–2024, https://doi.org/10.1093/infdis/jit431 (2013).
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