Author:
Sánchez-Sánchez Manuel,García Teodoro L.,Heredia Donají,Reséndiz Isaac,Cruz Lorena,Santiago Jacqueline,Rojas-Granados Adelina,Ubaldo-Reyes Laura,Pérez-Campos-Mayoral Laura,Pérez-Campos Eduardo,Vásquez Gervacio S.,Moguel Juan M.,Zarate Romeo,García Oscar,Sánchez Luisa,Torres Fernando,Paz Alberto,Elizarraras-Rivas Jesús,Hernández-Huerta María T.,Angeles-Castellanos Manuel
Abstract
AbstractThe Continuous bright light conditions to which premature infants are subjected while hospitalized in Neonatal Intensive Care Units (NICU) can have deleterious effects in terms of growth and development. This study evaluates the benefits of a light/darkness cycle (LDC) in weight and early hospital discharge from the NICU. Subjects were recruited from three participating institutions in Mexico. Eligible patients (n = 294) were premature infants who were hospitalized in the low-risk and high-risk neonatal units classified as stable. The subjects randomized to the experimental group (n = 150) were allocated to LDC conditions are as follows: light from 07:00 to 19:00 and darkness (25 lx) from 19:00 to 07:00. The control group (n = 144) was kept under normal room light conditions (CBL) 24 h a day. Main outcome was weight gain and the effect of reducing the intensity of nocturnal light in development of premature infants. Infants to the LDC gained weight earlier, compared with those randomized to CBL, and had a significant reduction in length of hospital stay. These results highlight those premature infants subjected to a LDC exhibit improvements in physiological development, favoring earlier weight gain and consequently a decrease in hospital stays. ClinicalTrials.gov; 02/09/2020 ID: NCT05230706.
Funder
FacMed-UNAM
Consejo Nacional de Ciencia y Tecnologia
Publisher
Springer Science and Business Media LLC
Cited by
4 articles.
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