Renal expression of JAK2 is high in polycystic kidney disease and its inhibition reduces cystogenesis
Author:
Funder
Kidney Research UK
University of Sheffield
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-019-41106-3.pdf
Reference47 articles.
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2. Carney, E. F. Polycystic kidney disease: TGF-beta signalling and vascular complications in ADPKD. Nat Rev Nephrol 9, 694, https://doi.org/10.1038/nrneph.2013.214 (2013).
3. Makabe, S. et al. Elevation of the serum liver enzyme levels during tolvaptan treatment in patients with autosomal dominant polycystic kidney disease (ADPKD). Clin Exp Nephrol. https://doi.org/10.1007/s10157-018-1545-7 (2018).
4. Jurenka, J. S. Anti-inflammatory properties of curcumin, a major constituent of Curcuma longa: a review of preclinical and clinical research. Altern Med Rev 14, 141–153 (2009).
5. Boyanapalli, S. S. S. et al. Pharmacokinetics and Pharmacodynamics of Curcumin in regulating anti-inflammatory and epigenetic gene expression. Biopharm Drug Dispos. https://doi.org/10.1002/bdd.2136 (2018).
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