Pharmacokinetics and Pharmacodynamics of Curcumin in regulating anti-inflammatory and epigenetic gene expression

Author:

Boyanapalli Sarandeep S.S.1,Huang Ying1,Su Zhengyuan1,Cheng David1ORCID,Zhang Chengyue1,Guo Yue1,Rao Rohit2,Androulakis Ioannis P.2,Kong Ah-NgORCID

Affiliation:

1. Department of Pharmaceutics, Ernest Mario School of Pharmacy, Rutgers; The State University of New Jersey; 160 Frelinghuysen Road Piscataway NJ 08854 USA

2. Department of Biomedical Engineering, Rutgers; The State University of New Jersey; Piscataway NJ USA

Funder

National Center for Complementary and Alternative Medicine

Publisher

Wiley

Subject

Pharmacology (medical),Pharmaceutical Science,Pharmacology,General Medicine

Reference41 articles.

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2. Pharmacology of Curcuma longa;Ammon;Planta Medica,1991

3. Curcumin promotes degradation of inducible nitric oxide synthase and suppresses its enzyme activity in RAW 264.7 cells;Ben;International Immunopharmacology,2011

4. Nrf2 knockout attenuates the anti-inflammatory effects of phenethyl isothiocyanate and curcumin;Boyanapalli;Chemical Research in Toxicology,2014

5. ‘Curcumin, the king of spices’: epigenetic regulatory mechanisms in the prevention of cancer, neurological, and inflammatory diseases;Boyanapalli;Current Pharmacology Reports,2015

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