Contribution of multidrug and toxin extrusion protein 1 (MATE1) to renal secretion of trimethylamine-N-oxide (TMAO)
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Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-018-25139-8.pdf
Reference45 articles.
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3. Tang, W. H. et al. Gut microbiota-dependent trimethylamine N-oxide (TMAO) pathway contributes to both development of renal insufficiency and mortality risk in chronic kidney disease. Circ Res 116, 448–455, https://doi.org/10.1161/CIRCRESAHA.116.305360 (2015).
4. Zeisel, S. H. & Warrier, M. Trimethylamine N-oxide, the microbiome, and heart and kidney disease. Annu Rev Nutr 37, 157–181, https://doi.org/10.1146/annurev-nutr-071816-064732 (2017).
5. Koeth, R. A. et al. Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis. Nature Med 19, 576–585, https://doi.org/10.1038/nm.3145 (2013).
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