Super-silent FRET Sensor Enables Live Cell Imaging and Flow Cytometric Stratification of Intracellular Serine Protease Activity in Neutrophils
Author:
Funder
Medical Research Council (MRC)
Engineering and Physical Sciences Research Council (EPSRC)
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-018-31391-9.pdf
Reference41 articles.
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2. Owen, C. A. & Campbell, E. J. The cell biology of leukocyte-mediated proteolysis. J. Leukoc. Biol. 65, 137–50 (1999).
3. Hirche, T. O. et al. Neutrophil Elastase Mediates Innate Host Protection against Pseudomonas aeruginosa. J. Immunol. 181, 4945–4954 (2008).
4. Lee, W. L. & Downey, G. P. Leukocyte elastase: physiological functions and role in acute lung injury. Am. J. Respir. Crit. Care Med. 164, 896–904 (2001).
5. Shapiro, S. D. Proteinases in chronic obstructive pulmonary disease. Biochem. Soc. Trans. 30, 98–102 (2002).
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