Amide-controlled, one-pot synthesis of tri-substituted purines generates structural diversity and analogues with trypanocidal activity-Reference-Cited by-同舟云学术

Amide-controlled, one-pot synthesis of tri-substituted purines generates structural diversity and analogues with trypanocidal activity

Published:2015-03-16 Issue:1 Volume:5 Page:
ISSN:2045-2322
Container-title:Scientific Reports
language:en
Short-container-title:Sci Rep

Author:

Pineda de las Infantas y Villatoro Maria J.,Unciti-Broceta Juan D.,Contreras-Montoya Rafael,Garcia-Salcedo Jose A.,Gallo Mezo Miguel A.,Unciti-Broceta Asier,Diaz-Mochon Juan J.

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/srep09139.pdf

Reference42 articles.

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2. Rosemeyer, H. The chemodiversity of purine as a constituent of natural products. Chem. and Biodivers. 1, 361–401 (2004).

3. Welsch, M. E., Zinder, S. A. & Stockwell, B. R. Privileged Scaffolds for Library Design and Drug Discovery. Curr. Opin. Chem. Biol. 14, 347–361 (2010).

4. Chang, Y. T. et al. Synthesis and application of functionally diverse 2,6,9-trisubstituted purine libraries as CDK inhibitors. Chem. Biol. 6, 361–375 (1999).

5. Jordheim, L. P., Durantel, P., Zoulim, F. & Dumontet, C. Advances in the development of nucleoside and nucleotide analogues for cancer and viral diseases. Nat. Rev. Drug Discov. 12, 447–64 (2013).

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