Systems-level metabolic flux profiling identifies fatty acid synthesis as a target for antiviral therapy-Reference-Cited by-同舟云学术

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Systems-level metabolic flux profiling identifies fatty acid synthesis as a target for antiviral therapy

Published:2008-09-28 Issue:10 Volume:26 Page:1179-1186
ISSN:1087-0156
Container-title:Nature Biotechnology
language:en
Short-container-title:Nat Biotechnol

Author:

Munger Joshua,Bennett Bryson D,Parikh Anuraag,Feng Xiao-Jiang,McArdle Jessica,Rabitz Herschel A,Shenk Thomas,Rabinowitz Joshua D

Publisher

Springer Science and Business Media LLC

Subject

Biomedical Engineering,Molecular Medicine,Applied Microbiology and Biotechnology,Bioengineering,Biotechnology

Link

http://www.nature.com/articles/nbt.1500.pdf

Reference58 articles.

1. Fiehn, O. Metabolomics–the link between genotypes and phenotypes. Plant Mol. Biol. 48, 155–171 (2002).

2. Nicholson, J.K., Connelly, J., Lindon, J.C. & Holmes, E. Metabonomics: a platform for studying drug toxicity and gene function. Nat. Rev. Drug Discov. 1, 153–161 (2002).

3. Sauer, U. Metabolic networks in motion: 13C-based flux analysis. Mol. Syst. Biol. 2, 62 (2006).

4. Wikoff, W.R., Gangoiti, J.A., Barshop, B.A. & Siuzdak, G. Metabolomics identifies perturbations in human disorders of propionate metabolism. Clin. Chem. 53, 2037–2039 (2007).

5. Holmes, E. et al. Metabolic profiling of CSF: evidence that early intervention may impact on disease progression and outcome in schizophrenia. PLoS Med. 3, e327 (2006).

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