Functional analysis of APOE locus genetic variation implicates regional enhancers in the regulation of both TOMM40 and APOE
Author:
Publisher
Springer Science and Business Media LLC
Subject
Genetics (clinical),Genetics
Link
http://www.nature.com/articles/jhg2011123.pdf
Reference33 articles.
1. Bekris, L. M., Yu, C. E., Bird, T. D. & Tsuang, D. W. Genetics of Alzheimer disease. J. Geriatr. Psychiatry Neurol. 23, 213–227 (2010).
2. Mahley, R. W., Weisgraber, K. H. & Huang, Y. Apolipoprotein E4: a causative factor and therapeutic target in neuropathology, including Alzheimer's disease. Proc. Natl Acad. Sci. USA 103, 5644–5651 (2006).
3. Coon, K. D., Myers, A. J., Craig, D. W., Webster, J. A., Pearson, J. V., Lince, D. H. et al. A high-density whole-genome association study reveals that APOE is the major susceptibility gene for sporadic late-onset Alzheimer's disease. J. Clin. Psychiatry 68, 613–618 (2007).
4. Yu, C. E., Seltman, H., Peskind, E. R., Galloway, N., Zhou, P. X., Rosenthal, E. et al. Comprehensive analysis of APOE and selected proximate markers for late-onset Alzheimer's disease: patterns of linkage disequilibrium and disease/marker association. Genomics 89, 655–665 (2007).
5. Hyman, B. T., Gomez-Isla, T., Rebeck, G. W., Briggs, M., Chung, H., West, H. L. et al. Epidemiological, clinical, and neuropathological study of apolipoprotein E genotype in Alzheimer's disease. Ann. N Y Acad. Sci. 802, 1–5 (1996).
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