The effect of NOD2 activation on TLR2-mediated cytokine responses is dependent on activation dose and NOD2 genotype
Author:
Publisher
Springer Science and Business Media LLC
Subject
Genetics (clinical),Genetics,Immunology
Link
http://www.nature.com/articles/gene20089.pdf
Reference17 articles.
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2. Hugot JP, Chamaillard M, Zouali H, Lesage S, Cezard JP, Belaiche J et al. Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease. Nature 2001; 411: 599–603.
3. Inohara N, Chamaillard M, McDonald C, Nunez G . NOD-LRR proteins: role in host-microbial interactions and inflammatory disease. Annu Rev Biochem 2005; 74: 355–383.
4. Bouma G, Strober W . The immunological and genetic basis of inflammatory bowel disease. Nat Rev Immunol 2003; 3: 521–533.
5. Inohara N, Ogura Y, Fontalba A, Gutierrez O, Pons F, Crespo J et al. Host recognition of bacterial muramyl dipeptide mediated through NOD2: implications for Crohn's disease. J Biol Chem 2003; 278: 5509–5512.
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