Targeted DNA demethylation in vivo using dCas9–peptide repeat and scFv–TET1 catalytic domain fusions-Reference-Cited by-同舟云学术

Targeted DNA demethylation in vivo using dCas9–peptide repeat and scFv–TET1 catalytic domain fusions

Published:2016-08-29 Issue:10 Volume:34 Page:1060-1065
ISSN:1087-0156
Container-title:Nature Biotechnology
language:en
Short-container-title:Nat Biotechnol

Author:

Morita Sumiyo,Noguchi Hirofumi,Horii Takuro,Nakabayashi Kazuhiko,Kimura Mika,Okamura Kohji^ORCID,Sakai Atsuhiko,Nakashima Hideyuki,Hata Kenichiro,Nakashima Kinichi,Hatada Izuho

Publisher

Springer Science and Business Media LLC

Subject

Biomedical Engineering,Molecular Medicine,Applied Microbiology and Biotechnology,Bioengineering,Biotechnology

Link

http://www.nature.com/articles/nbt.3658.pdf

Reference32 articles.

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3. Bird, A.P. & Wolffe, A.P. Methylation-induced repression--belts, braces, and chromatin. Cell 99, 451–454 (1999).

4. Feinberg, A.P. & Tycko, B. The history of cancer epigenetics. Nat. Rev. Cancer 4, 143–153 (2004).

5. Carey, N., Marques, C.J. & Reik, W. DNA demethylases: a new epigenetic frontier in drug discovery. Drug Discov. Today 16, 683–690 (2011).

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