ERMAP is a B7 family-related molecule that negatively regulates T cell and macrophage responses
Author:
Funder
U.S. Department of Health & Human Services | NIH | National Institute of Allergy and Infectious Diseases
Connecticut Innovations
Publisher
Springer Science and Business Media LLC
Subject
Infectious Diseases,Immunology,Immunology and Allergy
Link
http://www.nature.com/articles/s41423-020-0494-8.pdf
Reference60 articles.
1. Freeman, G. J. et al. Structure, expression, and T cell costimulatory activity of the murine homologue of the human B lymphocyte activation antigen B7. J. Exp. Med. 174, 625–631 (1991).
2. Freeman, G. J. et al. Cloning of B7-2: a CTLA-4 counter-receptor that costimulates human T cell proliferation. Science. 262, 909–911 (1993).
3. Dong, H., Zhu, G., Tamada, K. & Chen, L. B. 7-H. 1 a third member of the B7 family, co-stimulates T-cell proliferation and interleukin-10 secretion. Nat. Med. 5, 1365–1369 (1999).
4. Freeman, G. J. et al. Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation. J. Exp. Med. 192, 1027–1034 (2000).
5. Latchman, Y. et al. PD-L2 is a second ligand for PD-1 and inhibits T cell activation. Nat. Immunol. 2, 261–268 (2001).
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