Emerging therapeutic opportunities for integrin inhibitors
Author:
Publisher
Springer Science and Business Media LLC
Subject
Drug Discovery,Pharmacology,General Medicine
Link
https://www.nature.com/articles/s41573-021-00284-4.pdf
Reference210 articles.
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2. Hynes, R. O. Integrins: bidirectional, allosteric signaling machines. Cell 110, 673–687 (2002).
3. Faull, R. J. & Ginsberg, M. H. Inside-out signaling through integrins. J. Am. Soc. Nephrol. 7, 1091–1097 (1996).
4. Zhu, J. et al. Requirement of alpha and beta subunit transmembrane helix separation for integrin outside-in signaling. Blood 110, 2475–2483 (2007).
5. Shattil, S. J., Kim, C. & Ginsberg, M. H. The final steps of integrin activation: the end game. Nat. Rev. Mol. Cell. Biol. 11, 288–300 (2010).
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