Publisher
Springer Science and Business Media LLC
Subject
Drug Discovery,Pharmacology,General Medicine
Reference203 articles.
1. Santos, R. et al. A comprehensive map of molecular drug targets. Nat. Rev. Drug Discov. 16, 19–34 (2017). This detailed annotation of current FDA-approved drugs includes peptides targeting ~670 human genome-derived proteins mapped to therapeutic indications.
2. Hauser, A. S., Attwood, M. M., Rask-Andersen, M., Schioth, H. B. & Gloriam, D. E. Trends in GPCR drug discovery: new agents, targets and indications. Nat. Rev. Drug Discov. 16, 829–842 (2017). This report presents a comprehensive analysis of all FDA-approved drugs targeting GPCRs, lists novel agents in clinical trials and identifies potential new GPCRs without an approved drug.
3. Alexander, S. P. et al. The Concise Guide to Pharmacology 2017/18: G protein-coupled receptors. Br. J. Pharmacol. 176, S21–S141 (2019). This comprehensive, curated database incorporates the IUPHAR recommendations for the nomenclature of drug targets, including GPCRs, as well as quantitative information on interactions with approved medicines and experimental agents.
4. Davenport, A. P. et al. International Union of Basic and Clinical Pharmacology. LXXXVIII. G protein-coupled receptor list: recommendations for new pairings with cognate ligands. Pharmacol. Rev. 65, 967–986 (2013).
5. Wardman, J. H. et al. Identification of a small-molecule ligand that activates the neuropeptide receptor GPR171 and increases food intake. Sci. Signal. 9, ra55 (2016).
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