Engineering a Carbohydrate-processing Transglycosidase into Glycosyltransferase for Natural Product Glycodiversification
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/srep21051.pdf
Reference60 articles.
1. Zhang, C. et al. Exploiting the reversibility of natural product glycosyltransferase-catalyzed reactions. Science 313, 1291–1294 (2006).
2. Gantt, R. W., Peltier-Pain, P., Cournoyer, W. J. & Thorson, J. S. Using simple donors to drive the equilibria of glycosyltransferase-catalyzed reactions. Nat. Chem. Biol. 7, 685–691 (2011).
3. Williams, G. J., Goff, R. D., Zhang, C. & Thorson, J. S. Optimizing glycosyltransferase specificity via “hot spot” saturation mutagenesis presents a catalyst for novobiocin glycorandomization. Chem. & Biol. 15, 393–401 (2008).
4. Williams, G. J. & Thorson, J. S. A high-throughput fluorescence-based glycosyltransferase screen and its application in directed evolution. Nat. Protoc. 3, 357–362 (2008).
5. Williams, G. J., Zhang, C. & Thorson, J. S. Expanding the promiscuity of a natural-product glycosyltransferase by directed evolution. Nat. Chem. Biol. 3, 657–662 (2007).
Cited by 19 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Production of highly water-soluble genistein α-diglucoside using an engineered O-α-glycoligase with enhanced transglycosylation activity and altered substrate specificity;Food Chemistry;2024-03
2. Engineering the enzyme toolbox to tailor glycosylation in small molecule natural products and protein biologics;Protein Engineering, Design and Selection;2022-11-29
3. Enzymatic glucosylation of polyphenols using glucansucrases and branching sucrases of glycoside hydrolase family 70;Critical Reviews in Food Science and Nutrition;2021-12-15
4. Highly thermostable and promiscuous β-1,3-xylanasen designed by optimized ancestral sequence reconstruction;Bioresource Technology;2021-11
5. Bacterial α-Glucan and Branching Sucrases from GH70 Family: Discovery, Structure–Function Relationship Studies and Engineering;Microorganisms;2021-07-28
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3